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When you are reading, writing or actually doing medical practice many issues related to the physical wellbeing of people seem to always filter their way into what you read write and do. They never stop invading your privacy and sometimes you have to work long hours dealing with them. One of them of course is side effects that accompany treatments along with other issues that need to be minimized, prevented or eliminated. Read on for more info on how domperidone works.

What side effects result from domperidone?

First things first so let’s try to delve into the meaning of side effects. A side effect may be viewed as an unwanted response to the work of any medication which is taken by a person in prescribed dosages.

Like everything else connected with disease, side effects caused by medications such as domperidone may be mild or severe, temporary or permanent.

Even though this is the general result of taking medication, there are people or patients who don’t experience side effects when they take the domperidone medication.

People are usually wary of side effects and perhaps even you become concerned by their impacts on your life and business.

If that’s the case, you should conduct a detailed discussion of the risks and benefits of medication with your doctor or pharmacist.

Commons side effects

Over a period of time, about 1% of people who took domperidone reported the appearance of symptoms. However many of them proved manageable while some dissipated by themselves over time.

If you ever experience the side effects listed below which may be severe and troublesome to you, you should quickly contact your doctor. Your pharmacist may also be able to give you advice on how to manage side effects. Here they are:

• dry mouth
• migraine or very painful headache
• cramps in your abdominal area
• pain in your breast(s)
• skin rash
• nausea or dizziness
• headache
• diarrhea

Less common side effect

Even though the list of side effects given below don’t occur very often, they can cause more serious problems if they are not known by your doctor or if you fail to seek medical treatment.

Whenever any of the side effects listed below actually take place, you are advised to consult with your doctor as soon as possible:

• you experience a flow of breast milk from your nipple
• you feel strong palpitations of your heartbeat or pulse
• your menstrual cycles become irregular
• in males, the breast may start to swell.

When you are already taking this drug medication, you should cease taking it and immediately seek medical attention if the side effects mentioned below occur:

• a feeling of fainting or dizziness
• irregular beating of the heart
• if signs of allergic reaction such as hives (skin rash), breathing difficulties and swelling face or throat, take place.

Other side effects not listed among those given above may be experienced by some people when they take domperidone. When this happens while you are taking the drug medication and it causes you concern and bother, you should check with your doctor and discuss the matter.

What are the precautions for using domperidone?

• Before taking the medication – make sure you let your doctor know of any medical issues or allergies you may have experienced, medications you’re taking, if you are pregnant or breast-feeding your child or other important information concerning your health. Whatever decision the doctor makes will be based on the knowledge of these facts in connection to how you should use the domperidone drug medication.
• Heart issues and cardiac arrest – studies undertaken recently show that irregularities of heart rhythm that can result in cardiac arrest or sudden death can be higher in people who take more than 30mg of domperidone per day, or in people over 60 years of age. If for instance you have abnormal electrical heart activity such as QT prolongation, heart failure or low levels of magnesium or potassium in your blood, discuss with your doctor how the drug may impact your medical condition, which in turn will affect dosage and effectiveness of the medication and if there’s a need to monitor progress.
• Important knowledge – it’s important to know if you are using other medications for changing your heart’s electrical activity or increase the amount of domperidone in your blood. There are other medications out there such as sotalol, quinidine, thioridazine, chlorpromazine, pimozde and a host of other medications that can boost the risk of QT prolongation which is an abnormal heart rhythm and should not be used at the same time with domperidone if it can be avoided. You’ll be placed at more risk and complications when you take these other medications  if you:

• are a woman
• have nutritional issues
• have low calcium, potassium or magnesium levels
• you’ve experienced a stroke
• are older than 65 years of age
• you have a history of sudden cardiac death in your family
• you have a history of heart disease or irregular heart rhythms
• have a slow heart beat
• have a diabetic condition
• have QT prolongation

Your Hormone levels – Domperidone can increase the hormone prolactin in your body and if you’ve had many cases of breast cancer, you should ask your doctor concerning the risks and benefits from using the drug medication because usually, cancers of the breast are prolactin related.

Kidney function – if your kidneys aren’t functioning well, it may cause the accumulation of domperidone in the body and give rise to more side effects. If you have malfunctioning kidneys you should let your doctor know how the drug medication might affect your health condition, how your condition may affect the medicinal doses you take and whether special monitoring would be needed. It may be that you doctor will recommend you take a lower dose of the medication or take the medication only once or twice daily instead of three times per day.

Pregnancy – it’s not recommended that domperidone in taken during pregnancy unless the benefits are greater than the risks. Contact your doctor immediately when you become aware that you have become pregnant.

Breastfeeding – it’s known that the mediation can pass into breast milk hence if you are breastfeeding your child and taking domperidone at the same time, your baby may be affected. Talk to your doctor about whether you should continue to breastfeed your child.

Seniors – heart problems become greater in people as they grow older beyond 60 years of age and this includes heart attack when taking domperidone. You should know the benefits and risks of the medication so talk to your doctor about your issue.

Children – the effectiveness and safety of this drug medication for children have yet to be established.

Bottom line

This article has attempted to give the full picture of how the drug medication domperidone works for the general health benefit of those taking it. It’s true that the main work that the drug does to your body is to drive the internal bodily substances that navigate the long journey through the gastrointestinal tract. However, it also impacts other health problems and organs along the way in a variety of ways making it an ideal medication for patients.

If you do have problems with your gastrointestinal tract, it seems that the most effective treatment is domperidone but it may be that you know very little about this drug medication. Well, now that you know the treatment the next thing is to know as much as you can about domperidone especially about how it works so that you can become more confident about using the medication. Read on to gain more facts about it.

Stimulates movement in the gastrointestinal tract

Domperidone is a member of a group of drug medications known as dopamine antagonists.

Its main use is that of treating the slow movement of substances in the gastrointestinal tract that’s mainly caused by the presence of diabetes and gastritis or an inflammation of the lining of the stomach.

The healing powers of domperidone

Patients who are treated for gastrointestinal tract disorders are simultaneously relieved from symptoms of nausea and vomiting, bloating and a feeling of always being full.

Domperidone may also be used as a treatment for preventing stomach nausea and vomiting that usually result from people being treated with medications which are used to treat Parkinson’s disease.

The healing action of domperidone drug medication helps the stomach to quickly discharge its content and so prevent the onset of nausea and vomiting.

Domperidone may be presented under many brand names and also in several different forms but it’s also the case that a particular brand name may not be available in all the forms that you may have heard or even approved for all of the conditions discussed in this article.

The good news is that the drug medication is available and it has been proven to do the healing work it’s supposed to do.

Consulting your doctor is vital

It’s quite likely that your doctor may recommend that you use domperidone for other conditions instead of those listed in drug articles you’ve read elsewhere.

If that’s the case you need to eradicate any doubts you may have about the medication by discussing it with your doctor.

If you are not sure exactly why you are taking the medication, talk to your doctor about it so you can become familiar with the medication.

In any case it wouldn’t be wise to discontinue taking the medication without first consulting your doctor about your intention for doing so.

It’s also not advisable to give the treatment to someone else even if they have the same symptoms that you have.

The reason is that it may prove harmful to them if their own doctor didn’t prepare the prescription. That being the case they should obtain their prescription from their own doctor.

What form does the domperidone tablet have?

In addition to wanting to know how the medication works, it’s also useful to know in what form the drug medication assumes.

The form of the medication is a biconvex, white in color and film-coated tablet with a logo that depicts a
“P” over a “10” display on only one side of the tablet.

The logo signifies that the tablet contains 10mg of domperidone.

Not displayed are the non-medicinal ingredients such as lactose and cornstarch, microcrystalline cellulose, povidone, magnesium stearate, sodium docusate 85%-sodium benzoate 15% and others.

How to use domperidone tablets

Knowing how a medication works and how it’s used are what the user must know before the medication is actually ingested.

It would be good to know that domperidone is available as a 10mg tablet which is taken 15 to 30 minutes before sitting down to have a meal.

Dose

The maximum dose for one day has been set at 30mg per day which effectively means that users are expected to take 3 tablets every day which also represents the shortest possible time of treatment.

The actual potency of the medication on the patient once it’s taken depends on various factors such as body weight, medical condition of the patient and the influence of other medications.

Prescription

It should be noted that if your doctor prescribes a dose that’s different from what is described in this article, you shouldn’t alter the way you are taking the medication before you talk to your doctor who will issue instructions for you to follow.

Once you are given a prescription, you should strictly adhere to it but of course unforeseen things can happen

How to deal with missing doses

You may miss a dose in which case you should take the missed dose immediately when you remember it and then continue with your existing schedule.

If you also notice that your missed dose is to expire very soon, skip it and wait for your next dose, take it and then resume your normal schedule.

You may not double your dose in the hope of “catching up” on the dose you missed and whenever you are uncertain about this, consult with your doctor or pharmacist for advice.

Storing and disposing domperidone

For getting the best effective results from this drug medication, you should store domperidone in a place where light and moisture are absent and should not be within the reach of children.

When you want to dispose of any form of medication including drug medication such as domperidone, avoid throwing them into wastewater receptacles such as the sink, into the toilet or the garbage bin.

The best thing to do would be to ask your pharmacist to advise you on how to dispose of unneeded or expired medications.

Domperidone doesn’t work for everyone

While domperidone may be effective in challenging the malfunction in your gastrointestinal tract and can alleviate feelings of nausea and vomiting, not everyone can take it if they are:

• experiencing blocked stomach or intestines
• suffering from prolactinoma which is a tumor of the pituitary gland of the brain
• taking medications that result in QT prolongation
• prone to bleeding from intestinal or stomach bleeding
• suffering from moderate to severe liver impairment.
• personally allergic to domperidone or any of its ingredients
• using other medications that have similar family roots as ketoconazole, erythromycin, ritonavir or nefazodone
• experiencing QT prolongation (a kind of irregular heartbeat)
• suffering from cardiac disease such as heart failure
• experiencing anomalies of potassium, magnesium or calcium levels in the blood

Bottom Line

Knowing exactly how a drug medication such as domperidone actually works, is perhaps the best possible insurance there is against medical mishaps and is the best way for using the medication correctly, safely and effectively. In this article we’ve had a serious look at how domperidone works and have successfully responded to the question: How does domperidone work? in answering this question, we’ve provided information that will enable you to also know how the drug works.

Like most drug treatments such as domperidone, there’s always the specter of side effects, their potency on the body and how best to avoid or try to eliminate or minimize their influence as much as possible so that people can feel at ease when treated without worrying about the likely side effects that may appear. It’s no wonder that questions like: What are the side effects of domperidone, are often asked to indicate a genuine desire to know side effects and the need to protect oneself. Read on

All about the 10mg domperidone tablets

In this article we will take a look at the 10mg domperidone tablets in an effort to answer to topic not forgetting that the inclusion of other features of domperidone is essential for explaining the bigger picture.

Tablets

The domperidone 10mg tablet is produced as a white round biconvex tablet with the inscription “Dm 10” written on only one side.

Domperidone is prescribed for treating symptoms of nausea and vomiting

How the tablets are used

For best results, domperidone should be taken orally between 15 to 30 minutes before meals but if ingested before meals, the absorption of the medication into the body may be delayed.

It’s recommended that doses of the drug should be taken at the time specified and if a dose is missed, that dose should be dismissed and the scheduled dose continued. You shouldn’t “double” the dose so that you can make up for the dose you missed.

It has been established that the maximum duration for treatment using domperidone is only one week.

The domperidone tablet is given for treating adults and adolescents of 12 years of age or older and who weigh 35 kg or more.

Users should take only one 10mg tablet at intervals of 8 hours which gives a total dosage of 30mg per day.

Domperidone efficacy on children

The efficacy of domperidone on children of less than 12 years of age has not yet been conclusively established.

Similarly the successful effectiveness of domperidone on adolescents of 12 and more years has not yet been conclusively established.

Contraindications of domperidone

The term “contraindication” means that the use of something especially drug medications is inadvisable because it may cause an adverse response, for instance taking domperidone with aspirin is contraindicated.

In addition the contraindication of domperidone applies in the following situations:

• in patients suffering from moderate to severe hepatic (liver) problems.
• In patients who have long suffered from cardiac issues especially QTc patients with pronounced electrolyte disturbances or underlying cardiac diseases such as congestive heart failure.
• Combined application of domperidone with QT prolonging drugs except apomorphine.
• Interacted application of domperidone with CY3A4 inhibitors regardless of their effect on their QT prolonging effects.
• Where a patient has a high sensitivity to domperidone or any excipients.
• Where a prolactin-releasing pituitary tumor is the condition being treated.
• When the condition is associated with kidney problems

In any case, domperidone should not be used as a treatment for stimulating gastric motility if it can cause harm. It should also not be used to treat hemorrhaging of the gastro-intestinal tract, mechanical obstruction or perforation.

Warnings and precautions for using domperidone

Precautions related to the use of domperidone are essential to safeguard against the possible onslaught or causation and worsening of side effects. Here are some examples of medical situations that should encourage precautionary awareness.

Patients who have rare hereditary issues of intolerance to galactose found in milk sugar, absolute deficiency in lactase or deficiency of glucose-galactose malabsorption, should not be allowed to take domperidone.

Infant usage

During the first month of birth the risk of neurological side effects are greater in young children. This is because the metabolic functions and blood-brain barrier are not yet fully functional.

The appearance extrapyramidal symptoms may also be caused by overdosing of domperidone as well as other causes which should be prevented from taking place.

Kidney impairment

When severe kidney weakening occurs, there would be a need to prolong the usage of domperidone to counteract the severity of the impairment.

When this happens, a corresponding reduction of the frequency of domperidone dosing should be reduced from three to twice daily but this will depend on the severity of the renal impairment. The amount of the dose should also be reduced.

Effects on the heart and blood vessels

In medial parlance these are known as the cardiovascular effects some of which are highlighted below.

Domperidone has been associated with QT prolongation intervals on the electrocardiogram. However, during monitoring very rare cases of QT prolongation have been recorded in patients who take domperidone.

Reports have been submitted only on patients with exacerbating risk factors, abnormal ion found in body cells, blood or other natural occurring material and the simultaneous use of domperidone with some other medication.

Studies of disease origin and spread (epidemiology) show that domperidone has been associated with acute ventricular arrhythmias or sudden cardiac death with patients in the 60 years age group and above especially susceptible.

Patients who were taking more than 30mg doses of the drug were also susceptible as were patients who were also taking QT-prolonging drugs or CYP33A4 inhibitors.

Interactive use with apomorphine

Apomorphine is also a QT prolonging drug that can be used concomitantly with domperidone only if the benefits are greater than the risks involved from the combined usage.

The simultaneous use may also take place only if the precautions recommended for the combined application of the apomorphine SmPC are fulfilled to the letter.

It should be noted that the use of domperidone as a treatment should be immediately stopped if there are symptoms or signs appear which suggest that cardiac arrhythmia suddenly makes its presence and the patient should be allowed to consult their doctor.

Patients are strongly advised to immediately report any symptoms of any cardiac occurrence and they should also note that the 23mg domperidone tablet contains a very small 1millimeter of sodium per tablet which is a very negligible amount of sodium.

Bottom Line

While the side effects mentioned in this article appear more technical that those given elsewhere, they’re not difficult to understand by anyone with only a rudimentary knowledge of medicines and medical terms. What is more important is the ability to have a basic grasp and understanding of what a medication is, how to take it, the side effects it causes and the means of avoiding or minimizing their effects. That’s it in a nutshell!

Like most drug treatments such as domperidone, there’s always the specter of side effects, their potency on the body and how best to avoid or try to eliminate or minimize their influence as much as possible so that people can feel at ease when treated without worrying about the likely side effects that may appear. It’s no wonder that questions like: What are the side effects of domperidone, are often asked to indicate a genuine desire to know side effects and the need to protect oneself. Read on

All about the 10mg domperidone tablets

In this article we will take a look at the 10mg domperidone tablets in an effort to answer to topic not forgetting that the inclusion of other features of domperidone is essential for explaining the bigger picture.

Tablets

The domperidone 10mg tablet is produced as a white round biconvex tablet with the inscription “Dm 10” written on only one side.

Domperidone is prescribed for treating symptoms of nausea and vomiting

How the tablets are used

For best results, domperidone should be taken orally between 15 to 30 minutes before meals but if ingested before meals, the absorption of the medication into the body may be delayed.

It’s recommended that doses of the drug should be taken at the time specified and if a dose is missed, that dose should be dismissed and the scheduled dose continued. You shouldn’t “double” the dose so that you can make up for the dose you missed.

It has been established that the maximum duration for treatment using domperidone is only one week.

The domperidone tablet is given for treating adults and adolescents of 12 years of age or older and who weigh 35 kg or more.

Users should take only one 10mg tablet at intervals of 8 hours which gives a total dosage of 30mg per day.

Domperidone efficacy on children

The efficacy of domperidone on children of less than 12 years of age has not yet been conclusively established.

Similarly the successful effectiveness of domperidone on adolescents of 12 and more years has not yet been conclusively established.

Contraindications of domperidone

The term “contraindication” means that the use of something especially drug medications is inadvisable because it may cause an adverse response, for instance taking domperidone with aspirin is contraindicated.

In addition the contraindication of domperidone applies in the following situations:

• in patients suffering from moderate to severe hepatic (liver) problems.
• In patients who have long suffered from cardiac issues especially QTc patients with pronounced electrolyte disturbances or underlying cardiac diseases such as congestive heart failure.
• Combined application of domperidone with QT prolonging drugs except apomorphine.
• Interacted application of domperidone with CY3A4 inhibitors regardless of their effect on their QT prolonging effects.
• Where a patient has a high sensitivity to domperidone or any excipients.
• Where a prolactin-releasing pituitary tumor is the condition being treated.
• When the condition is associated with kidney problems

In any case, domperidone should not be used as a treatment for stimulating gastric motility if it can cause harm. It should also not be used to treat hemorrhaging of the gastro-intestinal tract, mechanical obstruction or perforation.

Warnings and precautions for using domperidone

Precautions related to the use of domperidone are essential to safeguard against the possible onslaught or causation and worsening of side effects. Here are some examples of medical situations that should encourage precautionary awareness.

Patients who have rare hereditary issues of intolerance to galactose found in milk sugar, absolute deficiency in lactase or deficiency of glucose-galactose malabsorption, should not be allowed to take domperidone.

Infant usage

During the first month of birth the risk of neurological side effects are greater in young children. This is because the metabolic functions and blood-brain barrier are not yet fully functional.

The appearance extrapyramidal symptoms may also be caused by overdosing of domperidone as well as other causes which should be prevented from taking place.

Kidney impairment

When severe kidney weakening occurs, there would be a need to prolong the usage of domperidone to counteract the severity of the impairment.

When this happens, a corresponding reduction of the frequency of domperidone dosing should be reduced from three to twice daily but this will depend on the severity of the renal impairment. The amount of the dose should also be reduced.

Effects on the heart and blood vessels

In medial parlance these are known as the cardiovascular effects some of which are highlighted below.

Domperidone has been associated with QT prolongation intervals on the electrocardiogram. However, during monitoring very rare cases of QT prolongation have been recorded in patients who take domperidone.

Reports have been submitted only on patients with exacerbating risk factors, abnormal ion found in body cells, blood or other natural occurring material and the simultaneous use of domperidone with some other medication.

Studies of disease origin and spread (epidemiology) show that domperidone has been associated with acute ventricular arrhythmias or sudden cardiac death with patients in the 60 years age group and above especially susceptible.

Patients who were taking more than 30mg doses of the drug were also susceptible as were patients who were also taking QT-prolonging drugs or CYP33A4 inhibitors.

Interactive use with apomorphine

Apomorphine is also a QT prolonging drug that can be used concomitantly with domperidone only if the benefits are greater than the risks involved from the combined usage.

The simultaneous use may also take place only if the precautions recommended for the combined application of the apomorphine SmPC are fulfilled to the letter.

It should be noted that the use of domperidone as a treatment should be immediately stopped if there are symptoms or signs appear which suggest that cardiac arrhythmia suddenly makes its presence and the patient should be allowed to consult their doctor.

Patients are strongly advised to immediately report any symptoms of any cardiac occurrence and they should also note that the 23mg domperidone tablet contains a very small 1millimeter of sodium per tablet which is a very negligible amount of sodium.

Bottom Line

While the side effects mentioned in this article appear more technical that those given elsewhere, they’re not difficult to understand by anyone with only a rudimentary knowledge of medicines and medical terms. What is more important is the ability to have a basic grasp and understanding of what a medication is, how to take it, the side effects it causes and the means of avoiding or minimizing their effects. That’s it in a nutshell!

Many people suffer from functional irregularities of the digestive system,that part of the human anatomywhich is perhaps its most important. It generates energy to make possible the functions of the rest of the body. Its importance is critical and its proper functioning even more so. This is why people ask:  What is domperidone tablets used for?  Read on to find out more on how the digestive system is treated by domperidone.

The medicinal uses of domperidone

Domperidone is used to increase the movements of substances through the digestive system of the body.

It’s also used as a treatment for symptoms of disorders in the stomach.

It may also be used to intervene and prevent the occurrence of nausea and vomiting which are triggered by the use of other medications.

Despite its many uses, domperidone may not be used by women engaged in breastfeeding in order to increase breast milk output due to certain safety concerns.

How domperidone is used

Taking the medication normally involves taking it in liquid form or in tablet form about 30 minutes before meals and when you go to bed at night.

Avoid increasing your dose above the amount prescribed for you and abstain from taking the drug medication more times than what the doctor has directed.

It doesn’t mean that your condition will improve much faster than you think but taking it more often will definitely increase the risk of side effects.

What are the side effects of domperidone?

The following are the different side effect caused by this drug medication:

• headache, dizziness, dry mouth, nervousness, flushing or irritability – these may occur after the first several days of taking domperidone
• inability to sleep, stomach cramps, hot flashes, leg cramps – these have been reported to take place after taking the drug. You should tell you doctor if these symptoms continue to bother you.
• chest pain, slow/fast/irregular heartbeat, swollen feet or ankles, , problems urinating swelling of the breast, discharge from thenipple in both men and women, changes in menstrual cycles, sexual issues – if you experience the above symptoms, you should immediately notify your doctor or pharmacist.

Precautionary measures

It’s imperative that you have direct contact with your doctor so that you are able to inform them of your medical history especially if you’ve had: a history of breast cancer or allergies

It’s also important if you can lower yourconsumption of alcoholicbeverages.

In the case ofpregnancy, domperidone may only be taken if there’s a clear need for taking it and there are no risks to the mother and her child.

You should fully discuss the various risks and benefits of taking the drug medication with your doctor.

Medical experts have found that domperidone can pass into a woman’s breast milk. This is a clear risk for the infant being nursed and therefore the use of the drug during breastfeeding is strongly not recommended.

You should talk to your doctor before you actually engage in breastfeeding.

Pregnancy and breastfeeding

Taking domperidone during pregnancy is not recommended and it’s strongly suggested you find out as much as you can on how domperidone can impact you and your baby during pregnancy from the website. “Best Use of Medicines in Pregnancy (BUMPS)

Breastfeeding and domperidone

Because domperidone can be passed into breast milk in small quantities, it should not be taken during breastfeeding. Consult with your doctor to find out all you can about the effects that the drug treatment may have on breastfeeding.

If the baby was prematurely born with low weight at birth or suffers from health complications, consult with your doctor before you take ant-sickness medication.

Supply of breast milk can be increased by domperidone but evidence also shows that it can also cause irregular heartbeat in a baby. Consult your doctor about benefits and risks of taking domperidone when you are breastfeeding.

Domperidone interaction with other drug medications

It’s clear that one of the most potent effects of the domperidone is in increasing movements of substances through the body’s digestive system.

This means that during the movement process, it’s possible that the drug may affect the absorption and movement of other medications through the body.

Because of this, it’s essential that you inform your doctor about any non-prescribed or prescribed medication which you have taken or intend to take, especially MAOI medications.

These would include furazolidone, phenelzine, selegiline and tranylcypromine. You definitely need the approval of your doctor or your pharmacist before you commence or end any medical treatment.

What about overdosing on domperidone?

If you realize that you’ve taken more domperidone than what has been prescribed for you, you should immediately contact the local poison control center or emergency room number in your area.

It doesn’t matter where you are when an overdose of domperidone has been taken. The most urgent thing to do is to be able to contact an emergency number for fast transportation to the nearest hospital or care center.

The symptoms that betray overdosing make themselves visible in the form of drowsiness, dizziness, confusion, irregular heartbeat, muscle cramps and twitching.

It’s also wise for you to attend periodical laboratory tests while you are taking so that the side effects can be detected and treated.

What happens if your missed a dose?

The moment you remember that you forgot to take your dose, you should take it the moment you remember.

If however, the time of your next dose is about to end, don’t take the missed tablet but wait for the time for taking the next tablet and take that dose instead.

You should not attempt to make ground for your “missed” dose by “doubling up” your dose so you can catch up.

Storing domperidone properly

The ideal storage method for domperidone should be at room temperature of between 59 and 86 degrees F (or 15 to 30 degrees C) clear of any heat or light and should definitely not be stored in the bathroom.

Bottom line

Knowing how a drug medication is used for treating conditions that affect our bodies is to travel one step closer to knowing whether or not the medication is in fact effective in treating the condition it’s supposed to treat. This article has gone further than that by providing insight into its side effects and when it should and shouldn’t be used as for example during pregnancy and how to take the medication properly by obeying instructions given by doctors and pharmacists.

When you discover a new drug medication such as Domperidone on which to write new content, there is always an urge to start from the very beginning and try to explain the various features of the medication so that not only the audience is treated to a new and interesting revelation but you yourself are enlightened about a topic you weren’t aware existed. So it is that we will start content on domperidone with a guide that will help readers fully understand the topic.

What is domperidone?

Domperidone is a medicine used as an anti-sickness treatment, especially when you want to stop feeling sick or you are actually being sick or vomiting.

The drug medication is also known by the brand name Motilium.

It can be used as a tablet or a liquid form that can be taken orally by patients and it’s available only with a prescription.

One of its main features is the ability to increase the supply of breast milk from women. It’s possible for your doctor to formulate a prescription if you have problems breastfeeding your child provided that other methods have failed.

Domperidone may also be used for treating stomach pain while you are given end of life care or palliative care.

Main features of domperidone

The medication is known to have the following main features:

• There are no strict rules surrounding its use which can take place whenever needed for up to three times a day.
• The best time to take domperidone is before you eat your meals.
• Normally a dry mouth is the most common side effect of domperidone
• Domperidone may only be provided on prescription for a short period of time (for about 1 week).

Who may or may not take domperidone

Adults and children of 12 years of age and over are permitted to take domperidone but sometimes it can be given on prescription to younger children by a specialist doctor.

However, domperidone has been regarded as unsuitable for some people.

Prior to taking the drug medication you must inform you doctor or pharmacist if you’ve experienced or is experiencing the following conditions in your life which have led you to:

• become allergic to domperidone or any other drug medication
• have heart issues, heartbeat irregularities, liver or heart problems.
• have Crohn’s disease or diverticulitis
• you’ve just undergone abdominal surgery perhaps for a hernia condition or for a caesarean birth.
• lose weight and is now below 35kg
• have bleeding from your gut or stomach areas.
• Have a tumour growth on your pituitary gland at the base of your brain

You should also note that domperidone has been known to be unsuitable for people who are aged 60 and above due to the occurrence of more serious side effects.

When and how to take domperidone

Before taking domperidone, you are strongly advised to strictly follow the directions given to you by your doctor.

Whenever you notice the appearance of symptoms to your body, you can then start to take the medication.

However, it’s recommended that you should take your domperidone tablet 15 to 30 minutes before you have your meal or snack.

When taking the domperidone tablets, you should take them whole orally with water and swallowing it but do not crush or chew it before taking them.

Domperidone in liquid form should be done with a provided syringe used for accurately measuring your dose. In the absence of a syringe, you should ask your pharmacist for the right spoon.

You should avoid using a spoon from your kitchen as it would most likely give you a wrong measurement and you may not get the correct dose.

The dosages

The normal dose for adults and children of 12 years of age and older, is one 10 mg tablet or if the treatment is given in liquid form, 10ml of liquid.

It’s permissible to take domperidone up to 3 times daily when you need it, but you should space the doses uniformly during the day by at least 8 hours apart between doses.

Forgetting to take your dose

If by any chance you forget to take your dose, you can do so the very moment you remember to take it, but if the missed dose  is about to expire, skip the dose you missed and take the next one in line at the appointed time.

Over dosing on domperidone

It has been found that an overdose of domperidone can be dangerous to your health and can also impact your life.

If you take more than your prescribed dose of domperidone, you may experience heart palpitations or irregular heartbeat.

If you advertently take an overdose of domperidone it’s strongly advisable to immediately call your doctor or the area emergency number.  

If your overdose condition requires you to go to A&E (Accident and Emergency) you should not try and drive yourself. Instead, get someone to drive you or opt to call an ambulance.

Make sure that you take the domperidone packet together with the leaflet in it and the remaining medication on your way to the A&E,

Side effects of domperidone

Like many drug medications domperidone can also have side effects but usually, not everyone taking it becomes affected by them.

The most common side effect of domperidone is that you usually get a dry mouth soon after taking it but it usually dissipates all by itself with time.

Serious side effects

In addition to the mild side effects, Domperidone can sometimes cause serious side effects which rarely occur. Make sure that you consult a doctor if:

• your eyes or muscles start to move in a weird or uncontrollable manner.
• you experience difficulty in urinating.

When you experience these symptoms, immediately call the area emergency number.

Serious allergic reaction

Although It’s very rare to get serious allergic response to domperidone, also known as anaphylaxis, it’s possible for some people to have this kind of reaction after taking the drug medication.

These allergic reactions are given below and If you happen to get them get them when taking domperidone, you should immediately call the area emergency number. Here are some of the main symptoms:

• skin rash accompanied by itchy, red, swollen, blistered or skin that peels away
• wheezing, especially by emitting a low “whistling” noise in rhyme with your breathing
• tightness in the chest or throat
• difficulty in talking or breathing
• swelling of the throat, tongue, lips, face or mouth.

If you want to know the complete list of serious side effects, you should refer to the leaflet inside the medical packet.

Coping with domperidone side effects

To be affected by the side effects of domperidone is fairly simple to deal with since the dryness of the mouth is the only common side effect that usually takes place. So what do you do about it?

Dry mouth – simply chew sugar-free gum or quietly suck on sugar free sweets.

Pregnancy and breastfeeding

Taking domperidone during pregnancy is not recommended and it’s strongly suggested you find out as much as you can on how domperidone can impact you and your baby during pregnancy from the website. “Best Use of Medicines in Pregnancy (BUMPS)

While domperidone can boost the amount of breast milk in a mother’s breast it can also result in irregular heartbeat in a baby. You need to consult your doctor about the risks and benefits of taking domperidone when you are breastfeeding.

Precautions when using domperidone with other medications

Domperidone and other medicines don’t interact well together and it may raise side effects issues.

Let your doctor or pharmacist know if you’re taking:

•  antidepressants or antipsychotic medications
•  fungal infection medications or antibiotics
• malaria-related medications
• HIV related medications
• medications for high blood pressure or heart problems
• cancer related medications

Should you take domperidone with other medicines?

The safest way is to take domperidone on its own when you are feeling sick or when you are actually being sick. If domperidone fails to work for you, speak to your doctor about it and follow their instructions.

Avoid using domperidone with herbal remedies as this may actually exacerbate the side effects.

Bottom line

There’s no denying the fact that a well written guide on a topic, which this time happens to be the drug medication domperidone, tends to result in complete satisfaction to readers who wish to know more about drug medications. Drugs have now become an integral part of the medical landscape and there’s little doubt that those who have taken this medication have experienced timely help, satisfaction and confidence in the types of treatment which are now available for healing patients.

Getting to know the right kind of medical information

If you were talking about the signs and symptoms of irritable bowel syndrome (IBS) it wouldn’t suffice if you simply used bullet points to convey a list of signs and symptoms in a cursory manner. A more effective method would be to discuss each one of the signs and symptoms in sufficient detail so that the what, when, who, where and why are presented clearly and succinctly providing pertinent information about IBS to the reader.

IBS Signs and Symptoms

Irritable bowel syndrome or IBS is suffered by between 6 – 18% of people globally.

The condition typically involves alterations in the frequency or type of bowel movement that is usually accompanied by abdominal pain.

Some of the factors that can trigger IBS include poor diet, stress and anxiety, poor sleep and changes in the bacteria population in your GI tract.

However, the factors that trigger this condition are not the same for every individual, stressors and anxiety factors involved.

This means that it’s very difficult to specifically name the foods or stress factors that people suffering from IBS should want to avoid.

In this article we shall discuss the most common symptoms of IBS and advise you on what you should do if you suspect that you are suffering from this condition. Here they are:

Pain and cramping

This is the key factor in diagnosing IBS and is the most common of all symptoms that help show you have the disease.

It’s medically known that your brain works together with your GI tract to control your digestion process.

This usually happens through hormones, nerves and messages that are released by the good bacteria residing in your digestive system.

In IBS, it’s these messages that become jumbled resulting in a painful tug-of-war tension in the muscles of your digestive tract.

The pain usually originates in the lower abdomen or in the entire abdomen but is very unlikely to happen only in the upper abdomen. The pain usually dissipates following a movement of your bowel.

Modification of your diet similar to a diet low in FODMAPs can usually improve the pain and other symptoms.

Other treatmentsthat are often used involve the use of bowel relaxants such as perppermint oil, hypnotherapy, and cognitive behavior therapy.

These treatments usually work in getting rid of the pain, but if they don’t stop the pain, a skilled gastroenterologist can assist you in finding a medication proven to have eased IBS pain.

Diarrhea

IBS with a diarrhea predominant tendency is one of three main kinds of disorder that affects one-third of patients suffering from IBS.

In a study conducted on 200 adults it was found that on average, patients with diarrhea-predominant IBS, had 12 weekly bowel movements, which was more than twice that of adults not affected by IBS.

An accelerated bowel transit in IBS patients may also induce a sudden and immediate urge for a bowel movement.

In these cases, patients describe the sensation as the a very strong source of stress that forces sufferers to forgo social functions because they fear a sudden onset of diarrhea.

Moreover, frequent loose stool which are common in IBS affected patients, are also a symptom of the diarrhea-predominant type.

Constipation

Even though it’s a little confusing, the fact is that IBS can cause bothconstipationas well as diarrhea.

However, the constipation-predominant IBS is usually the most common type that affects up to 50% of people who have IBS.

The altered messages communicated between the b rain and the bowel may result in the speeding up or slowing down of the normal transit period of stool.

It has been found that when the transit time is slowed down, the bowel absorbs more water from stool making it more difficult to move.

Constipation has been defined as having less than three bowel movements per week.

Another type of constipation – functional constipation – is also a chronic constipation but is not related to IBS even though it’s very common. It’s different from IBS because it’s not painful.

Constipation in IBS on the other hand is painful but eases when there are movements of the bowel.

Constipation in IBS also causes a feeling of having an incomplete bowel movement which can lead to unnecessary straining.

For easing your constipation, you should do exercise, drink more water, eat soluble fiber, take probiotics and a limited use of laxatives.

Alternating constipation and diarrhea

Sometimes you may experience mixed or alternating bowel movements of constipation and diarrhea that also impacts the lives of about 20% of patients suffering from IBS.

This occurrence of diarrhea and constipation in IBS usually involve chronic, recurring abdominal pain. The pain is a good indication that alterations in bowel movements are not diet related or are common, mild infections.

It’s known that this type of mixed IBS has the propensity to be even more severe than other types and usually have more frequent and intense symptoms.

It’s also important to note that these mixed IBS symptoms can also vary from one individual to another. This means that the condition needs to be treated separately for each patient rather than to use a “one-size-fits-all” approach.

Bowel movement changes

The slow movement of stool along the GI tract often allows the food to becomes dehydrated as water is absorbed by the intestine.

The absorption of water results in hard stool, which can worsen the symptoms of constipation.

The rapid passage of stool through the intestine doesn’t leave much time for water absorption and this inevitably result in in the loose stools that marks the onset of diarrhea.

It’s also medically known that IBS can be responsible for causing mucus to accumulate in stool, a process which is not normally associated with the causes of constipation.

The presence of blood in your stool may be a heads up on the presence of a potentially more serious underlying condition which warrants a visit to your doctor.

Usually, blood that appears in stool may appear red, but more often it will appear as a very black or black blotch with a tarry consistency.

Bottom line

The moment you go through information similar to that provided in this article, and you complete reading it to the end, you’ll no doubt feel that you’ve gotten more familiar with the irritable bowel syndrome IBS than you’ve ever had in your life. The good news about this is that you feel more confident in your ability to gain extra information you’ve never come across before and you feel less fearful about the irritable bowel syndrome or IBS condition which will get rid of some of your stress.

Two of the most important processes that relate to irritable bowel syndrome (IBS) is the diagnosis and the treatment that typically follows once all the needed medical information is available. These two procedures are extremely important for the effective treatment of IBS (and other conditions) and the ultimate relieving of pain found in those suffering from IBS. This article will attempt to explain both processes and add domperidone to the list of treatments available.

Diagnostic processes for IBS

Essentially, diagnosing IBS involves the exclusion of other GI disorders that can activate similar symptoms.

The first requirement is for the gathering of historic medical information so that the duration and frequency of the symptoms can be determined.

For the diagnosis to be successfully carried out, the symptom under scrutiny should remain diagnosable for at least six months and should take place at least three times every month.

Tests may be ordered by a doctor that can include tests of your stool, CT scans, orX-rays.

The main ideafor performing the tests is not for confirming a diagnosis of IBS, but to rule out other problems that can influence or change status quo for IBS.

Tests used  for IBS

These tests are relatively new blood tests that have the propensity to help diagnose IBS.

One of the tests involves testing for irritable bowel syndrome with diarrhea (IBS-D), and the other is for the testing of irritable bowel syndrome with both diarrhea and constipation (IBS-M ).

The point to note here is that these two tests aren’t able to diagnose irritable bowel syndrome (IBS-C)

Both these blood tests are to confirm the presence or otherwise of anti-CdtB and anti-vinculin antibodies.

Medical scientists believe that these antibodies are known to develop in some patients following a very bad attack of gastroenteritis caused by different common types of bacteria.

These bacteria can stage an overgrowth in the GI tract that can activate an immune attack on the intestinal tissues of the patient suffering from IBS.

This attack usually results in an inflammation and damage to the GI tract tissue giving rise to the appearance of IBS symptoms.

The tests may also help differentiate between irritable bowel syndrome and inflammatory bowel disease, or IBD, a different intestinal inflammatory disease that also includes Crohn’s disease and ulcerative colitis.

It appears that the antibody tests are useful in diagnosing irritable bowel syndrome with diarrhea IBS-D, but not the diagnosis of IBS with constipation (IBS-C).

It also seems that the tests are also IBS specific which means that when the antibodies are present, it’s  most likely that IBS is also present.

This means in effect that these two irritable bowel syndrome tests may in fact be trying to identify a subset of patients with IBS only, especially those who have post-infectious IBS.

It’s important to note that both these blood tests have not be subjected to extensive testing, have also not been given FDA approval partly because the test involved is expensive to patients who may have to spend a minimum of $500 to over $1,000.

Medications used for treating IBS

As already mentioned earlier, the three main types of IBS are irritable bowel syndrome with diarrhea (IBS-D), irritable bowel syndrome with constipation (IBS-C) and irritable bowel syndrome with alternating diarrhea and constipation or irritable bowel syndrome mixed (IBS-M)

We will focus attention on only two of the three IBS conditions, namely irritable bowel syndrome with diarrhea IBS-D and irritable bowel syndrome with constipation IBS-C.

Medications for IBS-D https://www.medicinenet.com/attapulgite/article.htm

These medications for treating diarrhea can include:

• Antidiarrheal medication that includeloperamide (Imodium),attapulgite (Kaopectate), diphenoxylate, and atgropine (lomotil) can be helpful in loose stools appear as one of the main signs.

A known prescription medication for irritable bowel syndrome with diarrhea (IBS-D) is eluxadoline (Viberzi)

• Females who suffer from IBS with severe diarrhea, medication alosetron  (lotronex) has been used for treatment.
• Another treatment for irritable bowel syndrome with diarrhea (IBS-D) and IBS-related bloating, is antibiotic Rifaximin (Xifaxan).
• Other medications such as cholestyramine (Prevalite), coletipol (collestid), or colesevelam (Welchol), can also help patients suffering from IBS-D but they can also cause bloating.

Medication for IBS-C

Medications used for treating constipation can include:

• OTC laxatives such as polyethylene glycol 3350 (Miralax), bisacodyl (Dulcolax) as well as psyllium seed husks (Metamucil)are able to relieve your constipation and regularize bowel movements.

Senna (Senokot, Ex-Lax Gentle Nature) laxatives is used for short-term treatment. Prescription laxatives such as lactulose (Constulose) may also be prescribed.

• Two other commonly used drugs for treating IBS are lubiprostone (Amitiza), a laxative, along with linaclotide (Linzess), a constipation medication.
• SSRI these includeantidepressants fluoxetine, citalopram, setiraline, paroxetine, and escitalopram, which may help those who have constipation (IBS-C), but they are known to also trigger IBS attacks in patients who have diarrhea (IBS-D).
• Domperidone is a prescribed medication that can also effectively treat IBS. Especially irritable bowel syndrome with constipation.
• This generic medication, that contains active ingredient domperidone, is also known by its brand name Motilium is also used for the treatment of people suffering from irritable bowel syndrome (IBS).
• If you are one of those suffering from IBS, domperidone may be the fight medication treatment for you.
• This active ingredient has the propensity to block the dopamine receptors in the upper part of your gastrointestinal tract.
• This interference can lead to an increased flurry of contractions of the stomach and bowel and by increasing these contractions Domperidone (Motilium) assists food to move more smoothly through the stomach.
• At the same time, domperidone can act to relieve nausea and vomiting usually associated with impaired digestion.
• Another benefit of Motilium (domperidone) is its anti-emetic drug that acts as a prokinetic agent that accelerates the digestive process thereby preventing a nauseous feeling.

Bottom line

Having access to appropriate treatments for chronic conditions such as irritable bowel syndrome in its several forms is an achievement that can greatly help in the efficacious treatment of IBS. In this article you are not only provided with information about the nature of this condition and how it’s diagnosed, but you are also provided with the different types of medications used for the treatment of IBS.

In so far as a healthy, virile, clean and normal functioning body is concerned, irritable bowel syndrome is perhaps the most dangerous and harmful condition that can infect your GI tract region and play havoc with the proper and effective functioning of your digestive system. There’s so much to learn about IBS but suffice it to say that if it can be treated effectively and safely, that would be fabulous don’t you think?

Efficacy of Domperidone

This generic medication is also known by its brand name Motilium and can also be used for the treatment of people suffering from irritable bowel syndrome (IBS).

If you are suffering from IBS, domperidone may be the right medication treatment for you.

It’s this active ingredient that has the propensity to block the dopamine receptors in the upper part of your gastrointestinal tract.

This interference can lead to increased contractions of the stomach and bowel and by increasing these contractions Domperidone (Motilium) assists food to move more smoothly through the stomach.

At the same time, Domperidone can act to relieve nausea and vomiting usually associated with impaired digestion.

Another benefit of Motilium (domperidone) is its anti-emetic drug that acts as a prokinetic agent that accelerates the digestive process thereby preventing a nauseous feeling.

What is IBS?

Simply put IBS, which is also known as spastic colon, can be defined as a kind of gastrointestinal disorder that has a variety of signs and symptoms that include:

• Abdominal pain
• Changed bowel habits
• Increase in bodilygas and release
• Bloatingor distention
• Cramping spasms
• Intolerance of food

Irritable bowel is a functional disorder which refers specifically to the alterations in the functioning of the digestive system which can result in the collection of symptoms referred to as IBS

Essentially, it’s a problem with the movement or ‘motility’ of substance in the gastrointestinal (GI) tract instead of any damage done to tissues of the digestive system.

It’s not possible to pinpoint the exact cause of irritable bowel syndrome but it’s sufficient to say that multiple factors may be responsible for causing its existence in your digestive system.

In the past, Irritable bowel syndrome was also known as spastic colon or bowel, functional bowel disease, mucous colitis, or nervous colon.

This functional disease has a variety of forms with diarrheafeaturing chronic or recurrent occurrences and constipation characterized by chronic abdominal painand discomfort.

Some people have the unenviable experience of having diarrhea and constipation inalternating sequence.

A diagnosis of IBS is usually based on the duration (of at least 6 months) and on the frequency of signs and symptoms (at least 3 times every month)

Some forms of IBS may be identified with the use of a new blood test.

The condition has no known cure but a variety of treatment options are available for the reduction or elimination of symptoms.

These treatments may include dietry changes, lifestyle changes, and prescription medications

There is no diet that’s specific to IBS and it should be noted that different people react to different types of foods.

For IBS sufferers, it’s important that they identify foods that can trigger their symptoms so that they can avoid them.

Generally speaking, people who suffer from IBS find that it helps to increase their intake of fiber, to  drink plenty of water, eat smaller portions of food, and to avoid soda.

The FODMAP diet for IBS

This stands for Fermentable, Oligosaccharides, Disaccharides, Monosaccharaides, and Polyols, which are made up of carbohydrates and sugar alcohols which the body can’t absorb completely, resulting in abdominal pain and bloating.

The FODMAPs can occur in both natural foods, or additives.

These foods can also cause:

• Pain
• Diarrhea
• Abdominal pain or distention
• Gas accumulation
• Bloating

The main characteristic of an irritable bowel syndrome is abdominal painand cramping but there are other symptoms and signs such as:

• Diarrhea: also referred to as IBS-Dcan occur suddenly urging one to have bowel movements in loose stool form.
• Constipation: also referred to as IBS-Cmay be accompanied by labored straining during bowel movements and infrequent stools.
• Increased gas accumulation
• Bloating or abdominal swelling
• Abdominal painthat causes discomfort
• Cramping pain following the consumption of certain food types
• Nausea
•  Foamy or mucous laden stool
•  Weight lossthat can’t be explained
•  Loss of appetite

Technically speaking, indigestionmay also be experienced but it has not be categorized as a symptom.

Very often, symptoms are very often relieved by the movements of the bowel.

Women who suffer from IBS have the propensity to have more symptoms during the monthly menstrual periods.

IBS risk factors

It is thought that the following risk factors have the propensity to cause IBS:

• Unusually strange movements of the small intestines and the colon that are sometimes too fast, or too slow, or too strong.
• A full bowel or high gas accumulation trigger hypersensitivity to pain
• Sensitivity to food, due mainly to poor absorption of acids and sugars in food
• Infection with gastroenteritis (also known as “stomach flu” or “stomach bug”), an invasion of the stomach and intestines by a viral or bacterial infection which may activate IBS symptoms.
• An onset of psychological conditions such as anxiety or depression
• Overgrowth of bacteria in the small intestine (SIBO)
• Although genetics has been thought to be a possible cause of IBS, it still needs to be proven.

What and how you eat can also have an impact on the symptoms of the IBS. While it’s impossible to totally prevent IBS symptoms, you should note that certain foods can activate IBS symptoms.

Your doctor may suggest that you keep a food diary so you can record the type of foods you consume and how they affect.

You should also know that some foods can actually help in preventing symptoms.

Beneficial foods to ingest

These food types may actually provide relief from the symptoms that can activate IBS in your GI tract. The foods include:

• Supplements of dietary fiber
• Water
• Foods high in carbohydrates such as brown rice, whole wheat pasta and whole grain breads,
• Probiotics that contain lactobacillus acidophilusand Bifidobacgterium, and prebiotics as well.
• Some people claim that kefir or Aloe Vera juice can help relieve symptoms. Don’t just take their words for it, but talk to your doctor and let him tell you about these home treatments.
• A diet rich in fiber that can help relieve some cases of IBS constipation, but be careful because this kind of diet may also exacerbate some of the symptoms such as gas accumulation and bloating.

Right now the recommended daily ingestion of fiber stands at 20 – 35 grams per day. However most people fail to achieve this intake but can still achieve relief from just a small increase in fiber intake.

Nevertheless, in order to maximize your benefit from fiber intake its best to increase your fiber intake in your diet gradually so as to reduce gas accumulation in your digestive system.

Harmful foods to avoid or minimize

The following foods should be avoided or minimized if you have IBS:

• Dairy products such as milk and cheese. The point to note here is that symptoms for lactose intolerancecan be the same as IBS symptoms.
• Vegetables that increase gas accumulation, such as Brussels sprouts, broccoli, cauliflower, and cabbage, should be taken in small amounts or totally avoided. Legumes such as beans are also included.
• Fried or fatty foods
• Caffeine, alcohol, or soda

Sugar saturated foods

• Artificial sweeteners
• Nuts
• Chewing gum

Bottom line

Irritable bowel syndrome or IBS can really spoil whatever you are doing or intend doing, This is the case if you have the unfortunate experience of having IBS-D which is that dreaded condition. The reason is that the urge to have a bowel movement is urgent but it can only offer temporary relief. Even so, the pain will reoccur and urge you to have another bowel movement for another temporary relief.