Stablon general information

What is Stablon used for?

Stablon tablets 12.5mg are used to treat major depression and reduce major depressive episodes ranging from mild to severe. Stablon 12.5 helps relieve symptoms of depressive illness, including anxiety, loss of interest in usual activities, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. Stablon tablets 12.5mg are also used as maintenance treatment for depression to prevent relapse or recurrence of depressive episodes.

How does Stablon work?

Stablon tablets 12.5mg contain tianeptine, an antidepressant belonging to the class of drugs known as selective serotonin reuptake enhancers (SSRE). Tianeptine is structurally similar to tricyclic antidepressants but has a different mechanism of action, which also differs from the selective serotonin reuptake inhibitors (SSRI). One of the major causes of depression is thought to be a lack of serotonin, a neurotransmitter or brain chemical that allows nerve cells to communicate, which controls many body activities, including regulating mood. Increasing serotonin is the target mechanism of most antidepressants. However, this does not appear to be the mechanism by which tianeptine exerts its antidepressive action. In contrast to the SSRI antidepressants that work by blocking the reuptake of serotonin from the synapse (gap between nerve cells across which chemical messages are sent) to make more serotonin available for nerve cell communication and increases stimulation of nerve p
athways that control mood, tianeptine in Stablon tablets 12.5mg increases the rate of serotonin reuptake by neurones. It is thought that the antidepressive action of tianeptine in Stablon tablets 12.5mg may be due to its effects on restoring neuronal neuroplasticity, which is the way nerve cells adapt to various stimuli and if impaired, areas of the brain associated with mood may change structurally. Thereby, tianeptine in Stablon tablets 12.5mg may reduce damage to the brain caused by stressful stimuli. Also tianeptine in Stablon tablets 12.5mg is thought to influence other neurotransmitter pathways that may affect mood, such as transmission of glutamate, which is the major excitatory neurotransmitter and is also involved in neurone plasticity. The actions of Stablon tablets 12.5mg contribute to relieving symptoms of depression and preventing depressive episodes.

What does Stablon contain?

Stablon tablets 12.5mg contain the active ingredient tianeptine, an antidepressant belonging to the class of drugs known as selective serotonin reuptake enhancers (SSRE) used to treat major depression.

Treating depression with Stablon

Stablon tablets 12.5mg contain tianeptine, an antidepressant belonging to the class of drugs known as selective serotonin reuptake enhancers (SSRE) that is used to treat major depression to reduce major depressive episodes ranging from mild to severe. Serotonin is a neurotransmitter or brain chemical that allows nerve cells to communicate, which controls many body activities, including regulating mood. Although one of the major causes of depression is thought to be a lack of serotonin, the mechanism of action of tianeptine in Stablon tablets 12.5mg suggests that other factors are involved in development of depression. Tianeptine is structurally similar to tricyclic antidepressants but has a different mechanism of action, which also differs from the selective serotonin reuptake inhibitors (SSRI). These antidepressants work by blocking the reuptake of serotonin from the synapse (gap between nerve cells across which chemical messages are sent), to make more serotonin available f
or nerve cell communication and increase stimulation of nerve pathways that control mood. In contrast, tianeptine in Stablon tablets 12.5mg increases the rate of serotonin reuptake by neurones. It is thought that the antidepressive action of tianeptine in Stablon tablets 12.5mg may be due to its effects on restoring neuronal neuroplasticity, which is the way nerve cells adapt to various stimuli and if impaired, areas of the brain associated with mood may change structurally. Thereby, tianeptine in Stablon tablets 12.5mg may reduce damage to the brain caused by stressful stimuli. Also tianeptine in Stablon tablets 12.5mg is thought to influence other neurotransmitter pathways that may influence mood, such as transmission of glutamate, which is the major excitatory neurotransmitter and is also involved in neurone plasticity. The actions of Stablon tablets 12.5mg contribute to relieving symptoms of depression including anxiety, loss of interest in usual activities, disturbed sl
eep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide.

What are the side effects of Stablon?

Stablon tablets 12.5mg is generally well tolerated compared with other antidepressants with reduced behavioural adverse effects; also reduced sleep, cardiovascular or bodyweight effects. The most commonly reported side effects when taking Stablon include nausea, diarrhoea, constipation, dry mouth, dizziness, drowsiness, headache.

When should Stablon not be used?

You should not use Stablon tablets 12.5mg if you:

• are allergic to tianeptine or any ingredients in Stablon
• are pregnant or are breastfeeding, without discussion with your doctor
• have kidney disease, without discussion with your doctor
• are taking any monoamine oxidase inhibitor medications as these can cause serious reactions if taken with Stablon or within 14 days
• are taking medicines that interact with Stablon, including other antidepressants such as, monoamine oxidase inhibitors (MAOIs), SSRIs, the tetracyclic antidepressant mianserine

How should Stablon be taken?

You should take your Stablon tablets 12.5mg swallowed whole with a glass of water, three times daily before a meal. You should continue to take your Stablon tablets 12.5mg for several weeks or months, depending on your condition and your doctor’s recommendations. Although you may start to improve within a few weeks, you should take your Stablon tablets 12.5mg regularly for as long as recommended by your doctor, usually at least 6 months even if you feel better, to ensure that you are free of symptoms.

How long should you take Stablon?

Although you may start to improve within a few weeks, you should take your Stablon tablets 12.5mg regularly for as long as recommended by your doctor, usually at least 6 months even if you feel better, to ensure that you are free of symptoms.

Missed dose of Stablon

If you miss a dose of Stablon tablets 12.5mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Stablon be stored?

You should store your Stablon tablets 12.5mg below 25°C in a cool dry place.